6RR7

Influenza A virus (A/NT/60/1968) polymerase Heterotrimer bound to 3'5' vRNA promoter and capped RNA primer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Polymerase acidic protein	polymer	716	83100.8	1	UniProt (P03434) Pfam (PF00603) In PDB	Influenza A virus (strain A/Northern Territory/60/1968 H3N2) (Influenza A virus (strain NT60))	RNA-directed RNA polymerase subunit P2
2	B	RNA-directed RNA polymerase catalytic subunit	polymer	757	86524.1	1	UniProt (P03432) Pfam (PF00602) In PDB	Influenza A virus (strain A/Northern Territory/60/1968 H3N2) (Influenza A virus (strain NT60))	Polymerase basic protein 1,PB1,RNA-directed RNA polymerase subunit P1
3	C	Polymerase basic protein 2	polymer	765	86958.2	1	UniProt (P03429) Pfam (PF20947) Pfam (PF20948) Pfam (PF20949) Pfam (PF20950) Pfam (PF00604) Pfam (PF20951) Pfam (PF20952) In PDB	Influenza A virus (strain A/Northern Territory/60/1968 H3N2) (Influenza A virus (strain NT60))	RNA-directed RNA polymerase subunit P3
4	F	RNA (5'-D(*(M7G))-R(P*AP*AP*UP*CP*U)-3')	polymer	6	1971.2	1		Spodoptera frugiperda
5	E	RNA (5'-R(P*GP*CP*CP*UP*GP*CP*UP*UP*UP*UP*G)-3')	polymer	14	4393.6	1		Influenza A virus (A/nt/60/1968(H3N2))
6	D	RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*C)-3')	polymer	15	4862.0	1		Influenza A virus (A/nt/60/1968(H3N2))

Sequence modifications

B: 1 - 757 (UniProt: P03432)

PDB	External Database	Details
Lys 577	Glu 577	conflict

C: 1 - 759 (UniProt: P03429)

PDB	External Database	Details
Glu 760	-	expression tag
Asn 761	-	expression tag
Leu 762	-	expression tag
Tyr 763	-	expression tag
Phe 764	-	expression tag
Gln 765	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	267809.9
All*	Total formula weight	267809.9

*Water molecules are not included.