6RQN
X-ray crystal structure of protiated (H) small monoclinic unit cell CA IX SV.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Carbonic anhydrase 9 | polymer | 256 | 28092.6 | 1 | UniProt (Q16790) Pfam (PF00194) In PDB | Homo sapiens (Human) | Carbonate dehydratase IX,Carbonic anhydrase IX,CAIX,Membrane antigen MN,P54/58N,Renal cell carcinoma-associated antigen G250,RCC-associated antigen G250,pMW1 |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
4 | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A: 140 - 395 (UniProt: Q16790)
PDB | External Database | Details |
---|---|---|
Ser 174 | Cys 174 | engineered mutation |
Ser 183 | Leu 183 | engineered mutation |
Lys 213 | Ala 213 | engineered mutation |
Lys 258 | Ala 258 | engineered mutation |
Tyr 259 | Phe 259 | engineered mutation |
Ser 350 | Met 350 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 28092.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 124.5 | |
All* | Total formula weight | 28217.0 |