6RPT
Structure of tick complement inhibitor CirpT1 complexed with macroglobubulin domain 4 of human complement C5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (E, A, C) | Complement C5 | polymer | 133 | 14511.4 | 3 | UniProt (P01031) Pfam (PF17789) | Homo sapiens (Human) | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 |
| 2 | B, D, F (F, B, D) | Putative 8.9 kDa family member | polymer | 113 | 12284.8 | 3 | UniProt (L7MB58) Pfam (PF15430) | Rhipicephalus pulchellus | |
| 3 | G, H, I, J, K (E, F, A, B, C) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 4 | L, M, N, O, P... (E, F, A, B, C...) | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
E, A, C: 348 - 460 (UniProt: P01031)
F, B, D: 4 - 92 (UniProt: L7MB58)
| PDB | External Database | Details |
|---|---|---|
| Met 328 | - | initiating methionine |
| Lys 329 | - | expression tag |
| His 330 | - | expression tag |
| His 331 | - | expression tag |
| His 332 | - | expression tag |
| His 333 | - | expression tag |
| His 334 | - | expression tag |
| His 335 | - | expression tag |
| Ser 336 | - | expression tag |
| Ala 337 | - | expression tag |
| Gly 338 | - | expression tag |
| Leu 339 | - | expression tag |
| Glu 340 | - | expression tag |
| Val 341 | - | expression tag |
| Leu 342 | - | expression tag |
| Phe 343 | - | expression tag |
| Gln 344 | - | expression tag |
| Gly 345 | - | expression tag |
| Pro 346 | - | expression tag |
| Met 347 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -20 | - | initiating methionine |
| Lys -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| Ser -12 | - | expression tag |
| Ala -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Glu -8 | - | expression tag |
| Val -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Phe -5 | - | expression tag |
| Gln -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Met -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Asp 1 | - | expression tag |
| Val 2 | - | expression tag |
| Gln 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 80388.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 460.5 | |
| All* | Total formula weight | 80849.2 |
