6RP9
Crystal structure of the T-cell receptor NYE_S3 bound to HLA A2*01-SLLMWITQV
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, F | HLA class I histocompatibility antigen, A-2 alpha chain | polymer | 277 | 32082.5 | 2 | UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) In PDB | Homo sapiens (Human) | MHC class I antigen A*2 |
2 | B, G | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
3 | C, H | Cancer/testis antigen 1 | polymer | 9 | 1090.3 | 2 | UniProt (P78358) In PDB | Homo sapiens | Autoimmunogenic cancer/testis antigen NY-ESO-1,Cancer/testis antigen 6.1,CT6.1,L antigen family member 2,LAGE-2 |
4 | D, I, K | T-cell receptor alpha chain | polymer | 206 | 22844.1 | 3 | Homo sapiens (Human) | ||
5 | E, J, L | T-cell receptor beta chain | polymer | 246 | 27621.6 | 3 | Homo sapiens (Human) |
Sequence modifications
A, F: 1 - 276 (UniProt: P01892)
B, G: 1 - 99 (UniProt: P61769)
C, H: 1 - 9 (UniProt: P78358)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
PDB | External Database | Details |
---|---|---|
Val 9 | Cys 165 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 241501.4 | |
All* | Total formula weight | 241501.4 |