6RP9

Crystal structure of the T-cell receptor NYE_S3 bound to HLA A2*01-SLLMWITQV

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, F (A, F)	HLA class I histocompatibility antigen, A-2 alpha chain	polymer	277	32082.5	2	UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439)	Homo sapiens (Human)	MHC class I antigen A*2
2	B, G (B, G)	Beta-2-microglobulin	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654)	Homo sapiens (Human)
3	C, H (C, H)	Cancer/testis antigen 1	polymer	9	1090.3	2	UniProt (P78358)	Homo sapiens	Autoimmunogenic cancer/testis antigen NY-ESO-1,Cancer/testis antigen 6.1,CT6.1,L antigen family member 2,LAGE-2
4	D, I, K (D, I, K)	T-cell receptor alpha chain	polymer	206	22844.1	3		Homo sapiens (Human)
5	E, J, L (E, J, L)	T-cell receptor beta chain	polymer	246	27621.6	3		Homo sapiens (Human)

Sequence modifications

A, F: 1 - 276 (UniProt: P01892)

PDB	External Database	Details
Met 0	-	initiating methionine

B, G: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

C, H: 1 - 9 (UniProt: P78358)

PDB	External Database	Details
Val 9	Cys 165	conflict

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	241501.4
All*	Total formula weight	241501.4

*Water molecules are not included.