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6RP8

Crystal Structure of Ipilimumab Fab complexed with CTLA-4 at 2.6A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(h, H)
Antibody Ipilimumab heavy chainpolymer22524232.12Homo sapiens (Human)
2B, D
(l, L)
Antibody Ipilimumab light chainpolymer21523477.02Homo sapiens (Human)
3E, F
(C, c)
Cytotoxic T-lymphocyte protein 4polymer11812637.42UniProt (P16410)
Pfam (PF07686)
Homo sapiens (Human)Cytotoxic T-lymphocyte-associated antigen 4,CTLA-4
4G, H
(l, H)
waterwater18.04Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight120693.2
All*Total formula weight120693.2
*Water molecules are not included.

249697

PDB entries from 2026-02-25

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