6RP6
Fragment AZ-019 binding at the TAZpS89/14-3-3 sigma interface
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
2 | P | WW domain-containing transcription regulator protein 1 | polymer | 13 | 1422.4 | 1 | UniProt (Q9GZV5) In PDB | Homo sapiens | Transcriptional coactivator with PDZ-binding motif |
3 | A | 4-phenyl-5-(piperidin-4-ylmethyl)thiophene-2-carboximidamide | non-polymer | 299.4 | 1 | Chemie (KDK) | |||
4 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
5 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
6 | water | water | 18.0 | 336 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Ala -3 | - | expression tag |
Met -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 27965.4 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 362.5 | |
All* | Total formula weight | 28327.9 |