6RO0
CRYSTAL STRUCTURE OF GENETICALLY DETOXIFIED PERTUSSIS TOXIN GDPT.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G (A, G) | Pertussis toxin subunit 1 | polymer | 269 | 29905.1 | 2 | UniProt (T1SR96) Pfam (PF02917) UniProt (by SIFTS) (P04977) | Bordetella pertussis | |
| 2 | B, H (B, H) | Islet-activating protein S2 | polymer | 226 | 24856.3 | 2 | UniProt (A0A0E8DFW5) Pfam (PF03440) Pfam (PF02918) UniProt (by SIFTS) (P04978) | Bordetella pertussis | Pertussis toxin subunit 2 |
| 3 | C, I (C, I) | Islet-activating protein S3 | polymer | 227 | 25012.8 | 2 | UniProt (Q546I1) Pfam (PF03440) Pfam (PF02918) UniProt (by SIFTS) (P04979) | Bordetella pertussis | Pertussis toxin subunit,Pertussis toxin subunit 3,Pertussis toxin subunit PtxC,Toxin subunit 3 |
| 4 | D, E, J, K (D, E, J, K) | Islet-activating protein S4 | polymer | 152 | 16566.7 | 4 | UniProt (C0MPK8) Pfam (PF09275) UniProt (by SIFTS) (P0A3R5) | Bordetella pertussis | Pertussis toxin subunit 4,Pertussis toxin subunit PtxD |
| 5 | F, L (F, L) | Pertussis toxin subunit 5 | polymer | 133 | 14513.8 | 2 | UniProt (C0MPK9) Pfam (PF09276) UniProt (by SIFTS) (P04981) | Bordetella pertussis | Pertussis toxin subunit PtxE |
| 6 | M, N, O, P, Q... (A, B, D, F, H...) | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 7 | AA, BA, CA, DA, EA... (F, G, H, I, J...) | water | water | 18.0 | 524 | Chemie (HOH) |
Sequence modifications
A, G: -33 - 235 (UniProt: T1SR96)
| PDB | External Database | Details |
|---|---|---|
| Lys 9 | Arg 43 | engineered mutation |
| Gly 129 | Glu 163 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 254842.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 828.8 | |
| All* | Total formula weight | 255671.8 |
