6RNE
DPP1 in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dipeptidyl peptidase 1 | polymer | 119 | 13500.2 | 1 | UniProt (P53634) Pfam (PF08773) | Homo sapiens (Human) | Cathepsin C,Cathepsin J,Dipeptidyl peptidase I,DPPI,Dipeptidyl transferase |
| 2 | B (B) | Dipeptidyl peptidase 1 | polymer | 165 | 18630.0 | 1 | UniProt (P53634) Pfam (PF00112) | Homo sapiens (Human) | Cathepsin C,Cathepsin J,Dipeptidyl peptidase I,DPPI,Dipeptidyl transferase |
| 3 | C (C) | Dipeptidyl peptidase 1 | polymer | 69 | 7583.4 | 1 | UniProt (P53634) | Homo sapiens (Human) | Cathepsin C,Cathepsin J,Dipeptidyl peptidase I,DPPI,Dipeptidyl transferase |
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E, J (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | F, G, K, L (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
| 7 | H (B) | (2~{S},4~{S})-~{N}-[(2~{S})-1-azanyl-3-[4-(4-cyanophenyl)phenyl]propan-2-yl]-4-fluoranyl-pyrrolidine-2-carboxamide | non-polymer | 366.4 | 1 | Chemie (KA8) | |||
| 8 | I (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 9 | M, O (B, C) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 10 | N (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 11 | P, Q, R (A, B, C) | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 39713.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1381.0 | |
| All* | Total formula weight | 41519.1 |
