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6RN8

RIP2 Kinase Catalytic Domain complex with 2(4[(1,3benzothiazol5yl)amino]6(2methylpropane2sulfonyl)quinazolin7yl)oxy)ethyl phosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Receptor-interacting serine/threonine-protein kinase 2polymer31135683.02UniProt (O43353)
Pfam (PF07714)
Homo sapiens (Human)CARD-containing interleukin-1 beta-converting enzyme-associated kinase,CARD-containing IL-1 beta ICE-kinase,RIP-like-interacting CLARP kinase,Receptor-interacting protein 2,RIP-2,Tyrosine-protein kinase RIPK2
2C, E
(A, B)
2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethyl dihydrogen phosphatenon-polymer538.52Chemie (K9T)
3D
(B)
CALCIUM IONnon-polymer40.11Chemie (CA)
4F, G
(A, B)
waterwater18.0306Chemie (HOH)
Sequence modifications
A, B: 1 - 310 (UniProt: O43353)
PDBExternal DatabaseDetails
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight71366.0
Non-Polymers*Number of molecules3
Total formula weight1117.1
All*Total formula weight72483.1
*Water molecules are not included.

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PDB entries from 2025-07-16

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