6RKQ
Crystal Structure of TGT in complex with N2-methyl-8-(prop-1-yn-1-yl)-3H,7H,8H-imidazo[4,5-g]quinazoline-2,6-diamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Queuine tRNA-ribosyltransferase | polymer | 375 | 41763.5 | 1 | UniProt (P28720) Pfam (PF01702) | Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) | Guanine insertion enzyme,tRNA-guanine transglycosylase |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | (8~{R})-~{N}2-methyl-8-prop-1-ynyl-7,8-dihydro-3~{H}-imidazo[4,5-g]quinazoline-2,6-diamine | non-polymer | 254.3 | 1 | Chemie (K75) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | F (A) | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence modifications
A: 10 - 384 (UniProt: P28720)
| PDB | External Database | Details |
|---|---|---|
| Lys 312 | Thr 312 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41763.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 489.9 | |
| All* | Total formula weight | 42253.4 |
