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6RIN

Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex bound to GreB transcription factor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(N)
Non-template DNApolymer3911962.71Escherichia coli
2B
(T)
Template DNApolymer3912065.71Escherichia coli
3C
(F)
Transcription elongation factor GreBpolymer15818573.11UniProt (C3SQ22)
Pfam (PF03449)
Pfam (PF01272)
UniProt (by SIFTS) (P30128)
Escherichia coli K12Transcript cleavage factor GreB
4D, E
(A, B)
DNA-directed RNA polymerase subunit alphapolymer32936558.72UniProt (P0A7Z4)
Pfam (PF01193)
Pfam (PF01000)
Pfam (PF03118)
Escherichia coli (strain K12)RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
5F
(C)
DNA-directed RNA polymerase subunit betapolymer1342150820.91UniProt (P0A8V2)
Pfam (PF04560)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF10385)
Pfam (PF00562)
Escherichia coli (strain K12)RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
6G
(D)
DNA-directed RNA polymerase subunit beta'polymer1407155366.81UniProt (P0A8T7)
Pfam (PF04997)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Escherichia coli (strain K12)RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta'
7H
(E)
DNA-directed RNA polymerase subunit omegapolymer9110249.51UniProt (P0A800)
Pfam (PF01192)
Escherichia coli (strain K12)RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
8I
(R)
RNApolymer144441.61Escherichia coli
9J, K
(D)
ZINC IONnon-polymer65.42Chemie (ZN)
10L
(D)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains9
Total formula weight436597.7
Non-Polymers*Number of molecules3
Total formula weight155.1
All*Total formula weight436752.9
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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