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6RHW

Crystal structure of human CD11b I-domain (CD11b-I) in complex with Staphylococcus aureus octameric bi-component leukocidin LukGH

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(G)
Beta-channel forming cytolysinpolymer30935625.31UniProt (A0A0D6HCK9)
Pfam (PF07968)
UniProt (by SIFTS) (Q2FWP0)
Staphylococcus aureusBi-component leukocidin LukGH subunit G,Gamma-hemolysin component B,Gamma-hemolysin subunit B
2B
(H)
Beta-channel forming cytolysinpolymer32437682.71UniProt (A0A0D6HC73)
Pfam (PF07968)
UniProt (by SIFTS) (Q2FWN9)
Staphylococcus aureusBi-component leukocidin LukGH subunit H,Leukocidin S subunit,Succinyl-diaminopimelate desuccinylase
3C
(C)
Integrin alpha-Mpolymer19522293.41UniProt (P11215)
Pfam (PF00092)
Homo sapiens (Human)CD11 antigen-like family member B,CR-3 alpha chain,Cell surface glycoprotein MAC-1 subunit alpha,Leukocyte adhesion receptor MO1,Neutrophil adherence receptor
4D, E, F, G, H...
(G, H)
DIMETHYL SULFOXIDEnon-polymer78.16Chemie (DMS)
5J
(H)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
6K
(C)
waterwater18.02Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight95601.4
Non-Polymers*Number of molecules7
Total formula weight493.1
All*Total formula weight96094.5
*Water molecules are not included.

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PDB entries from 2026-01-21

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