6RHV
Crystal structure of mouse CD11b I-domain (CD11b-I) in complex with Staphylococcus aureus octameric bi-component leukocidin LukGH (LukH K319A mutant)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | G | Beta-channel forming cytolysin | polymer | 309 | 35625.3 | 1 | UniProt (A0A0D6HCK9) Pfam (PF07968) UniProt (by SIFTS) (Q2FWP0) In PDB | Staphylococcus aureus | Bi-component leukocidin LukGH subunit G,Gamma-hemolysin component B,Gamma-hemolysin subunit B |
2 | H | Beta-channel forming cytolysin | polymer | 324 | 37624.6 | 1 | UniProt (A0A0D6HC73) Pfam (PF07968) UniProt (by SIFTS) (Q2FWN9) In PDB | Staphylococcus aureus | Bi-component leukocidin LukGH subunit H,Leukocidin S subunit,Succinyl-diaminopimelate desuccinylase |
3 | C | Integrin alpha-M | polymer | 195 | 22143.1 | 1 | UniProt (P05555) Pfam (PF00092) In PDB | Mus musculus (Mouse) | CD11 antigen-like family member B,CR-3 alpha chain,Cell surface glycoprotein MAC-1 subunit alpha,Leukocyte adhesion receptor MO1 |
4 | G, H, C | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 6 | Chemie (DMS) | |||
5 | H | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
6 | water | water | 18.0 | 356 | Chemie (HOH) |
Sequence modifications
H: 1 - 324 (UniProt: A0A0D6HC73)
PDB | External Database | Details |
---|---|---|
Ala 319 | Lys 346 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 95393.0 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 493.1 | |
All* | Total formula weight | 95886.1 |