6RHV
Crystal structure of mouse CD11b I-domain (CD11b-I) in complex with Staphylococcus aureus octameric bi-component leukocidin LukGH (LukH K319A mutant)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | Beta-channel forming cytolysin | polymer | 309 | 35625.3 | 1 | UniProt (A0A0D6HCK9) Pfam (PF07968) UniProt (by SIFTS) (Q2FWP0) | Staphylococcus aureus | Bi-component leukocidin LukGH subunit G,Gamma-hemolysin component B,Gamma-hemolysin subunit B |
| 2 | B (H) | Beta-channel forming cytolysin | polymer | 324 | 37624.6 | 1 | UniProt (A0A0D6HC73) Pfam (PF07968) UniProt (by SIFTS) (Q2FWN9) | Staphylococcus aureus | Bi-component leukocidin LukGH subunit H,Leukocidin S subunit,Succinyl-diaminopimelate desuccinylase |
| 3 | C (C) | Integrin alpha-M | polymer | 195 | 22143.1 | 1 | UniProt (P05555) Pfam (PF00092) | Mus musculus (Mouse) | CD11 antigen-like family member B,CR-3 alpha chain,Cell surface glycoprotein MAC-1 subunit alpha,Leukocyte adhesion receptor MO1 |
| 4 | D, E, F, G, H... (G, H, C) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 6 | Chemie (DMS) | |||
| 5 | I (H) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | K, L, M (G, H, C) | water | water | 18.0 | 356 | Chemie (HOH) |
Sequence modifications
H: 1 - 324 (UniProt: A0A0D6HC73)
| PDB | External Database | Details |
|---|---|---|
| Ala 319 | Lys 346 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 95393.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 493.1 | |
| All* | Total formula weight | 95886.1 |
