6RHC
Fragment AZ-003 binding at the TAZpS89/14-3-3 sigma interface
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (P) | WW domain-containing transcription regulator protein 1 | polymer | 13 | 1422.4 | 1 | UniProt (Q9GZV5) | Homo sapiens | Transcriptional coactivator with PDZ-binding motif |
| 3 | C, D, H (A, P) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | E, F (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | G (A) | 5-azanyl-4-phenyl-thiophene-2-carboximidamide | non-polymer | 217.3 | 1 | Chemie (K48) | |||
| 6 | I, J (A, P) | water | water | 18.0 | 294 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27965.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 361.1 | |
| All* | Total formula weight | 28326.5 |
