6RGT
Crystal structure of the cofactor-free Aspergillus flavus urate oxidase T57A variant anaerobically complexed with 9-methyl uric acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Uricase | polymer | 302 | 34258.7 | 1 | UniProt (Q00511) Pfam (PF01014) | Aspergillus flavus | Urate oxidase |
| 2 | B (A) | 9-METHYL URIC ACID | non-polymer | 182.1 | 1 | Chemie (MUA) | |||
| 3 | C (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 4 | D, E (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 5 | F (A) | water | water | 18.0 | 597 | Chemie (HOH) |
Sequence modifications
A: 0 - 301 (UniProt: Q00511)
| PDB | External Database | Details |
|---|---|---|
| Ala 57 | Thr 58 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34258.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 544.6 | |
| All* | Total formula weight | 34803.3 |
