6RFD
Cryo-EM structure of the N-terminal DC repeat (NDC) of NDC-NDC chimera (human sequence) bound to 14-protofilament GDP-microtubule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, a) | Tubulin alpha-1B chain | polymer | 432 | 48263.6 | 2 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | C, D (B, b) | Tubulin beta-2B chain | polymer | 429 | 48113.1 | 2 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | |
| 3 | E (N) | Neuronal migration protein doublecortin | polymer | 99 | 11441.8 | 1 | UniProt (O43602) Pfam (PF03607) | Homo sapiens (Human) | Doublin,Lissencephalin-X,Lis-X |
| 4 | F, H (A, a) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 5 | G, I (A, a) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | J, K (B, b) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) |
Sequence modifications
A, a: 1 - 441 (UniProt: P81947)
B, b: 1 - 429 (UniProt: Q6B856)
| PDB | External Database | Details |
|---|---|---|
| - | Ser 38 | deletion |
| - | Asp 39 | deletion |
| - | Lys 40 | deletion |
| - | Thr 41 | deletion |
| - | Ile 42 | deletion |
| - | Gly 43 | deletion |
| - | Gly 44 | deletion |
| - | Gly 45 | deletion |
| - | Asp 46 | deletion |
| PDB | External Database | Details |
|---|---|---|
| Ala 55 | Thr 55 | conflict |
| Val 170 | Met 170 | conflict |
| Ala 296 | Ser 296 | conflict |
| Val 316 | Ile 316 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 204195.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1981.4 | |
| All* | Total formula weight | 206176.7 |
