6RFD
Cryo-EM structure of the N-terminal DC repeat (NDC) of NDC-NDC chimera (human sequence) bound to 14-protofilament GDP-microtubule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, a) | Tubulin alpha-1B chain | polymer | 432 | 48263.6 | 2 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | C, D (B, b) | Tubulin beta-2B chain | polymer | 429 | 48113.1 | 2 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | |
| 3 | E (N) | Neuronal migration protein doublecortin | polymer | 99 | 11441.8 | 1 | UniProt (O43602) Pfam (PF03607) | Homo sapiens (Human) | Doublin,Lissencephalin-X,Lis-X |
| 4 | F, H (A, a) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 5 | G, I (A, a) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 6 | J, K (B, b) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) |
Sequence modifications
A, a: 1 - 441 (UniProt: P81947)
B, b: 1 - 429 (UniProt: Q6B856)
| PDB | External Database | Details |
|---|---|---|
| - | Ser 38 | deletion |
| - | Asp 39 | deletion |
| - | Lys 40 | deletion |
| - | Thr 41 | deletion |
| - | Ile 42 | deletion |
| - | Gly 43 | deletion |
| - | Gly 44 | deletion |
| - | Gly 45 | deletion |
| - | Asp 46 | deletion |
| PDB | External Database | Details |
|---|---|---|
| Ala 55 | Thr 55 | conflict |
| Val 170 | Met 170 | conflict |
| Ala 296 | Ser 296 | conflict |
| Val 316 | Ile 316 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 204195.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1981.4 | |
| All* | Total formula weight | 206176.7 |
