6RBJ
Crystal structure of KDM3B in complex with 5-(1H-tetrazol-5-yl)quinolin-8-ol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Lysine-specific demethylase 3B | polymer | 351 | 40521.8 | 2 | UniProt (Q7LBC6) Pfam (PF02373) | Homo sapiens (Human) | JmjC domain-containing histone demethylation protein 2B,Jumonji domain-containing protein 1B,Nuclear protein 5qNCA |
| 2 | C, D, H, I, J (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 3 | E, K (A, B) | 5-(1~{H}-1,2,3,4-tetrazol-5-yl)quinolin-8-ol | non-polymer | 213.2 | 2 | Chemie (JX8) | |||
| 4 | F, L (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | G (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, B: 1380 - 1728 (UniProt: Q7LBC6)
| PDB | External Database | Details |
|---|---|---|
| Ser 1378 | - | expression tag |
| Met 1379 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 81043.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 882.1 | |
| All* | Total formula weight | 81925.6 |
