6RAF

Heterodimeric ABC exporter TmrAB in inward-facing narrow conformation under turnover conditions

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Multidrug resistance ABC transporter ATP-binding and permease protein	polymer	623	70664.8	1	UniProt (Q72J05) Pfam (PF00664) Pfam (PF00005) In PDB	Thermus thermophilus HB27
2	B	Multidrug resistance ABC transporter ATP-binding and permease protein	polymer	578	64634.5	1	UniProt (Q72J04) Pfam (PF00664) Pfam (PF00005) In PDB	Thermus thermophilus
3	C	Anti-vesicular stomatitis virus N VHH	polymer	136	14594.4	1	UniProt (A0A192B6J5) Pfam (PF07686) In PDB	Vicugna pacos (Alpaca)
4	A	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)
5	B	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
6	B	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)

Sequence modifications

A: 1 - 600 (UniProt: Q72J05)

PDB	External Database	Details
Lys 601	-	expression tag
Leu 602	-	expression tag
Gly 603	-	expression tag
Gly 604	-	expression tag
Gly 605	-	expression tag
Gly 606	-	expression tag
Glu 607	-	expression tag
Asn 608	-	expression tag
Leu 609	-	expression tag
Tyr 610	-	expression tag
Phe 611	-	expression tag
Gln 612	-	expression tag
Gly 613	-	expression tag
His 614	-	expression tag
His 615	-	expression tag
His 616	-	expression tag
His 617	-	expression tag
His 618	-	expression tag
His 619	-	expression tag
His 620	-	expression tag
His 621	-	expression tag
His 622	-	expression tag
His 623	-	expression tag

C: 1 - 124 (UniProt: A0A192B6J5)

PDB	External Database	Details
Met -1	-	initiating methionine
Ala 0	-	expression tag
Pro 14	Ala 14	conflict
Asp 16	Gly 16	conflict
Arg 19	Thr 19	conflict
Ala 23	Val 23	conflict
Val 24	Ala 24	conflict
Ser 27	Arg 27	conflict
Ala 28	Pro 28	conflict
Leu 29	Phe 29	conflict
Asp 30	Arg 30	conflict
Tyr 31	Asn 31	conflict
Asn 32	Tyr 32	conflict
Ala 33	Arg 33	conflict
Ile 34	Leu 34	conflict
Gly 47	Phe 47	conflict
Cys 50	Ala 50	conflict
Ser 52	Asn 52	conflict
Lys 53	Trp 53	conflict
Ile 54	Gly 54	conflict
Thr 55	Gly 55	conflict
Gly 56	Val 56	conflict
Asn 57	Ile 57	conflict
Ala 59	Asn 59	conflict
Asn 74	Asp 74	conflict
His 80	Tyr 80	conflict
Asp 90	Glu 90	conflict
Thr 98	Ala 98	conflict
Val 99	Phe 99	conflict
Thr 100	Asp 100	conflict
Ala 101	Ser 101	conflict
Val 102	Thr 102	conflict
Leu 103	Gly 103	conflict
Leu 104	Ser 104	conflict
Gly 106	Ile 106	conflict
Arg 107	Val 107	conflict
Cys 108	Arg 108	conflict
Val 109	Asp 109	conflict
Pro 110	Asn 110	conflict
Gly 111	Tyr 111	conflict
Lys 112	Glu 112	conflict
Pro 119	Gln 119	conflict
His 125	-	expression tag
His 126	-	expression tag
His 127	-	expression tag
His 128	-	expression tag
His 129	-	expression tag
His 130	-	expression tag
Glu 131	-	expression tag
Pro 132	-	expression tag
Glu 133	-	expression tag
Ala 134	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	149893.7
Non-Polymers*	Number of molecules	3
	Total formula weight	958.7
All*	Total formula weight	150852.3

*Water molecules are not included.