6R7K
Ligand complex of RORg LBD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear receptor ROR-gamma | polymer | 283 | 32909.8 | 1 | UniProt (P51449) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | B (C) | SRC2 peptide | polymer | 15 | 1838.2 | 1 | UniProt (by SIFTS) (Q15596) | Homo sapiens (Human) | |
| 3 | C (A) | (2~{R})-2-(4-ethylsulfonylphenyl)-~{N}-[4-[1,1,1,3,3,3-hexakis(fluoranyl)-2-oxidanyl-propan-2-yl]phenyl]-2-(2-phenylethanoylamino)ethanamide | non-polymer | 602.5 | 1 | Chemie (JUH) | |||
| 4 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | F, G (A, C) | water | water | 18.0 | 296 | Chemie (HOH) |
Sequence modifications
A: 265 - 507 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Met 243 | - | initiating methionine |
| His 244 | - | expression tag |
| Asn 245 | - | expression tag |
| His 246 | - | expression tag |
| Asn 247 | - | expression tag |
| His 248 | - | expression tag |
| Asn 249 | - | expression tag |
| His 250 | - | expression tag |
| Asn 251 | - | expression tag |
| His 252 | - | expression tag |
| Asn 253 | - | expression tag |
| His 254 | - | expression tag |
| Asn 255 | - | expression tag |
| Gly 256 | - | expression tag |
| Gly 257 | - | expression tag |
| Glu 258 | - | expression tag |
| Asn 259 | - | expression tag |
| Leu 260 | - | expression tag |
| Tyr 261 | - | expression tag |
| Phe 262 | - | expression tag |
| Gln 263 | - | expression tag |
| Gly 264 | - | expression tag |
| Gly 508 | - | expression tag |
| Gly 509 | - | expression tag |
| Gly 510 | - | expression tag |
| Lys 511 | - | expression tag |
| Glu 512 | - | expression tag |
| Lys 513 | - | expression tag |
| His 514 | - | expression tag |
| Lys 515 | - | expression tag |
| Ile 516 | - | expression tag |
| Leu 517 | - | expression tag |
| His 518 | - | expression tag |
| Arg 519 | - | expression tag |
| Leu 520 | - | expression tag |
| Leu 521 | - | expression tag |
| Gln 522 | - | expression tag |
| Asp 523 | - | expression tag |
| Ser 524 | - | expression tag |
| Ser 525 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34747.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 703.7 | |
| All* | Total formula weight | 35451.6 |
