6R4W
Crystal structure of apo PPEP-1(E143A/Y178F) in complex with substrate peptide Ac-EVNAPVP-CONH2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Pro-Pro endopeptidase | polymer | 198 | 21909.6 | 2 | UniProt (Q183R7) Pfam (PF07737) | Peptoclostridium difficile | PPEP-1,Zinc metalloprotease Zmp1 |
| 2 | C, D (C, D) | ACE-GLU-VAL-ASN-ALA-PRO-VAL-LPD | polymer | 8 | 749.9 | 2 | Clostridioides difficile | ||
| 3 | E, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 446 | Chemie (HOH) |
Sequence modifications
A, B: 27 - 220 (UniProt: Q183R7)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
| Ser 24 | - | expression tag |
| His 25 | - | expression tag |
| Met 26 | - | expression tag |
| Ala 143 | Glu 143 | conflict |
| Phe 178 | Tyr 178 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 45319.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 45449.8 |
