6R4M

Crystal structure of S. cerevisia Niemann-Pick type C protein NPC2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Phosphatidylglycerol/phosphatidylinositol transfer protein	polymer	201	21813.6	3	UniProt (Q12408) Pfam (PF02221)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	PG/PI-TP,NPC2 homolog
2	D, E, F (A, B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A, B, C: 1 - 173 (UniProt: Q12408)

PDB	External Database	Details
Leu 174	-	expression tag
Val 175	-	expression tag
Pro 176	-	expression tag
Arg 177	-	expression tag
Gly 178	-	expression tag
Ser 179	-	expression tag
Gly 180	-	expression tag
Gly 181	-	expression tag
Gly 182	-	expression tag
Gly 183	-	expression tag
Ser 184	-	expression tag
Gly 185	-	expression tag
Gly 186	-	expression tag
Gly 187	-	expression tag
Gly 188	-	expression tag
Ser 189	-	expression tag
Gly 190	-	expression tag
Gly 191	-	expression tag
His 192	-	expression tag
His 193	-	expression tag
His 194	-	expression tag
His 195	-	expression tag
His 196	-	expression tag
His 197	-	expression tag
His 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag
His 201	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	65440.9
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	66104.5

*Water molecules are not included.