6R2F

Crystal structure of TEX12 F102A F109E V116A in an alternative conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Testis-expressed protein 12	polymer	79	8981.1	4	UniProt (Q9BXU0) Pfam (PF15219) In PDB	Homo sapiens (Human)
2	A, B, C, D	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	11	Chemie (MPD)
3	A, D	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4		water	water		18.0	145	Chemie (HOH)

Sequence modifications

A, B, C, D: 49 - 123 (UniProt: Q9BXU0)

PDB	External Database	Details
Gly 45	-	expression tag
Ser 46	-	expression tag
Met 47	-	expression tag
Gly 48	-	expression tag
Ala 102	Phe 102	engineered mutation
Glu 109	Phe 109	engineered mutation
Ala 116	Val 116	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	35924.4
Non-Polymers*	Number of molecules	13
	Total formula weight	1370.8
All*	Total formula weight	37295.2

*Water molecules are not included.