6R1C
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 12a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Cereblon isoform 4 | polymer | 125 | 13703.6 | 3 | UniProt (A4TVL0) | Magnetospirillum gryphiswaldense MSR-1 | |
| 2 | D (A) | ASPARTIC ACID | non-polymer | 133.1 | 1 | Chemie (ASP) | |||
| 3 | E, H, M (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | F, N (A, C) | S-Thalidomide | non-polymer | 258.2 | 2 | Chemie (EF2) | |||
| 5 | G, K, L (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 6 | I (B) | 4-[[4-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyloxymethyl]phenyl]methylamino]-4-oxidanylidene-butanoic acid | non-polymer | 377.3 | 1 | Chemie (JOW) | |||
| 7 | J (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | O, P, Q (A, B, C) | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 124 (UniProt: A4TVL0)
| PDB | External Database | Details |
|---|---|---|
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 41110.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1543.5 | |
| All* | Total formula weight | 42654.2 |
