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6R18

Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 11a

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Cereblon isoform 4polymer12513703.63UniProt (A4TVL0)Magnetospirillum gryphiswaldense MSR-1
2D
(D)
Cereblon isoform 4polymer3273.31Magnetospirillum gryphiswaldense MSR-1
3E, H, L
(A, B, C)
ZINC IONnon-polymer65.43Chemie (ZN)
4F, M
(A, C)
S-Thalidomidenon-polymer258.22Chemie (EF2)
5G, J, N
(A, B, D)
PHOSPHATE IONnon-polymer95.03Chemie (PO4)
6I
(B)
[4-(aminomethyl)phenyl]methyl ~{N}-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamatenon-polymer277.31Chemie (JOQ)
7K
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
8O, P, Q, R
(A, B, C, D)
waterwater18.0281Chemie (HOH)
Sequence modifications
A, B, C: 1 - 124 (UniProt: A4TVL0)
PDBExternal DatabaseDetails
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight41384.1
Non-Polymers*Number of molecules10
Total formula weight1310.3
All*Total formula weight42694.4
*Water molecules are not included.

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PDB entries from 2026-03-11

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