6R16

Crystal structure of the SUN1-KASH4 6:6 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	SUN domain-containing protein 1	polymer	203	22530.4	6	UniProt (O94901) Pfam (PF07738)	Homo sapiens (Human)	Protein unc-84 homolog A,Sad1/unc-84 protein-like 1
2	G, H, I, J, K... (G, H, I, J, K...)	Nesprin-4	polymer	32	3303.9	6	UniProt (Q8N205) Pfam (PF10541)	Homo sapiens (Human)	KASH domain-containing protein 4,KASH4,Nuclear envelope spectrin repeat protein 4
3	M, O, P, R, T... (A, B, C, D, E...)	POTASSIUM ION	non-polymer		39.1	6	Chemie (K)
4	N, Q, S (B, D, E)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
5	V, W, X (G, H, I)	ZINC ION	non-polymer		65.4	3	Chemie (ZN)
6	AA, BA, CA, DA, EA... (C, D, E, F, G...)	water	water		18.0	90	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 616 - 812 (UniProt: O94901)

PDB	External Database	Details
Gly 610	-	expression tag
Ser 611	-	expression tag
Gly 612	-	expression tag
Gly 613	-	expression tag
Ser 614	-	expression tag
Gly 615	-	expression tag

G, H, I, J, K, L: 376 - 404 (UniProt: Q8N205)

PDB	External Database	Details
Gly 373	-	expression tag
Ser 374	-	expression tag
Met 375	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	155005.4
Non-Polymers*	Number of molecules	12
	Total formula weight	617.0
All*	Total formula weight	155622.4

*Water molecules are not included.