6QXU
Human TNKS1 in complex with 6,8-Difluoro-2-[4-(1-hydroxy-1-methyl-ethyl)-phenyl]-3H-quinazolin-4-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Poly [ADP-ribose] polymerase tankyrase-1 | polymer | 211 | 24212.5 | 1 | UniProt (O95271) Pfam (PF00644) In PDB | Homo sapiens (Human) | ADP-ribosyltransferase diphtheria toxin-like 5,ARTD5,Poly [ADP-ribose] polymerase 5A,Protein poly-ADP-ribosyltransferase tankyrase-1,TNKS-1,TRF1-interacting ankyrin-related ADP-ribose polymerase,Tankyrase I,Tankyrase-1,TANK1 |
| 2 | A | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 3 | A | 6,8-bis(fluoranyl)-2-[4-(2-oxidanylpropan-2-yl)phenyl]-3~{H}-quinazolin-4-one | non-polymer | 316.3 | 1 | Chemie (JKN) | |||
| 4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | water | water | 18.0 | 335 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24212.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 459.8 | |
| All* | Total formula weight | 24672.3 |
