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6QXT

Cas1-Cas2-Csn2-DNA dimer complex from the Type II-A CRISPR-Cas system

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, AA, B, BA, C...
(A, B, C, D, E...)
CRISPR-associated protein Csn2polymer21925533.516UniProt (G3ECR4)
Pfam (PF09711)
Streptococcus thermophilus
2I, IA, J, JA, L...
(I, J, L, M, O...)
CRISPR-associated endonuclease Cas1polymer30235363.524UniProt (G3ECR2)
Pfam (PF01867)
Streptococcus thermophilus
3K, KA, N, NA, Q...
(K, N, Q, T, W...)
CRISPR-associated endoribonuclease Cas2polymer11413431.612UniProt (G3ECR3)
Pfam (PF09827)
Streptococcus thermophilus
4AB
(1)
DNA (64-MER)polymer6419423.41Escherichia coli BL21(DE3)
5BB
(2)
DNA (64-MER)polymer6420000.31Escherichia coli BL21(DE3)
6CB, DB, EB, FB, GB...
(A, B, E, F, a...)
CALCIUM IONnon-polymer40.116Chemie (CA)
Sequence modifications
I, J, L, M, O, P, R, S, U, V, Y, Z, i, j, l, m, o, p, r, s, u, v, y, z: 1 - 289 (UniProt: G3ECR2)
PDBExternal DatabaseDetails
Leu 290-expression tag
Glu 291-expression tag
Ser 292-expression tag
Gly 293-expression tag
Trp 294-expression tag
Ser 295-expression tag
His 296-expression tag
Pro 297-expression tag
Gln 298-expression tag
Phe 299-expression tag
Glu 300-expression tag
Lys 301-expression tag
Ala 302-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains54
Total formula weight1457861.0
Non-Polymers*Number of molecules16
Total formula weight641.2
All*Total formula weight1458502.2
*Water molecules are not included.

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PDB entries from 2024-11-06

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