6QUT
Three dimensional structure of human carbonic anhydrase IX in complex with benzenesulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Carbonic anhydrase 9 | polymer | 251 | 27550.1 | 4 | UniProt (Q16790) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase IX,Carbonic anhydrase IX,CAIX,Membrane antigen MN,P54/58N,Renal cell carcinoma-associated antigen G250,RCC-associated antigen G250,pMW1 |
| 2 | E, G, I, L (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F, H, J, K, M... (A, B, C, D) | 4-chloranyl-~{N}-(3-oxidanylpropyl)-2-phenylsulfanyl-5-sulfamoyl-benzamide | non-polymer | 400.9 | 6 | Chemie (J8N) | |||
| 4 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 735 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 5 - 257 (UniProt: Q16790)
| PDB | External Database | Details |
|---|---|---|
| Ser 41 | Cys 174 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 110200.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2667.0 | |
| All* | Total formula weight | 112867.3 |
