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6QRM

HsNMT1 in complex with both MyrCoA and GNCFSKRRAA substrates

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BGlycylpeptide N-tetradecanoyltransferase 1polymer40246465.42UniProt (P30419)
Pfam (PF01233)
Pfam (PF02799)
In PDB
Homo sapiens (Human)Myristoyl-CoA:protein N-myristoyltransferase 1,Type I N-myristoyltransferase,Peptide N-myristoyltransferase 1
2C, DApoptosis-inducing factor 3polymer101112.32UniProt (Q96NN9)
In PDB
Homo sapiensApoptosis-inducing factor-like protein
3ACOENZYME Anon-polymer767.51Chemie (COA)
4A, BGLYCEROLnon-polymer92.14Chemie (GOL)
5A, BCHLORIDE IONnon-polymer35.52Chemie (CL)
6BTETRADECANOYL-COAnon-polymer977.91Chemie (MYA)
7CMYRISTIC ACIDnon-polymer228.41Chemie (MYR)
8waterwater18.0396Chemie (HOH)
Sequence modifications
A, B: 99 - 496 (UniProt: P30419)
PDBExternal DatabaseDetails
Gly 95-expression tag
Gly 96-expression tag
Ser 97-expression tag
Glu 98-expression tag
C, D: 1 - 10 (UniProt: Q96NN9)
PDBExternal DatabaseDetails
Asn 2Gly 3engineered mutation
Arg 7Pro 8engineered mutation
Arg 8Lys 9conflict
Ala 9Pro 10conflict
Ala 10Val 11conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight95155.4
Non-Polymers*Number of molecules9
Total formula weight2413.1
All*Total formula weight97568.5
*Water molecules are not included.

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PDB entries from 2024-07-10

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