6QRM
HsNMT1 in complex with both MyrCoA and GNCFSKRRAA substrates
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Glycylpeptide N-tetradecanoyltransferase 1 | polymer | 402 | 46465.4 | 2 | UniProt (P30419) Pfam (PF01233) Pfam (PF02799) In PDB | Homo sapiens (Human) | Myristoyl-CoA:protein N-myristoyltransferase 1,Type I N-myristoyltransferase,Peptide N-myristoyltransferase 1 |
2 | C, D | Apoptosis-inducing factor 3 | polymer | 10 | 1112.3 | 2 | UniProt (Q96NN9) In PDB | Homo sapiens | Apoptosis-inducing factor-like protein |
3 | A | COENZYME A | non-polymer | 767.5 | 1 | Chemie (COA) | |||
4 | A, B | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
6 | B | TETRADECANOYL-COA | non-polymer | 977.9 | 1 | Chemie (MYA) | |||
7 | C | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) | |||
8 | water | water | 18.0 | 396 | Chemie (HOH) |
Sequence modifications
A, B: 99 - 496 (UniProt: P30419)
C, D: 1 - 10 (UniProt: Q96NN9)
PDB | External Database | Details |
---|---|---|
Gly 95 | - | expression tag |
Gly 96 | - | expression tag |
Ser 97 | - | expression tag |
Glu 98 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Asn 2 | Gly 3 | engineered mutation |
Arg 7 | Pro 8 | engineered mutation |
Arg 8 | Lys 9 | conflict |
Ala 9 | Pro 10 | conflict |
Ala 10 | Val 11 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 95155.4 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 2413.1 | |
All* | Total formula weight | 97568.5 |