6QR8
Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | tRNA (guanine-N(1)-)-methyltransferase | polymer | 244 | 26434.7 | 2 | UniProt (B1MDI3) Pfam (PF01746) In PDB | Mycobacterium abscessus | M1G-methyltransferase,tRNA [GM37] methyltransferase |
2 | A, B | 5-azanyl-3-[1-[[4-[(4-methylpiperazin-1-yl)methyl]phenyl]methyl]indol-6-yl]-1~{H}-pyrazole-4-carbonitrile | non-polymer | 425.5 | 2 | Chemie (JDH) | |||
3 | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 242 (UniProt: B1MDI3)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 52869.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 851.1 | |
All* | Total formula weight | 53720.4 |