6QQO

Aplysia californica AChBP in complex with 2-Fluoro-(carbamoylpyridinyl)deschloroepibatidine analogue (3)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Soluble acetylcholine receptor	polymer	249	28326.8	10	UniProt (Q8WSF8) Pfam (PF02931) In PDB	Aplysia californica (California sea hare)
2	C, J, G, D, A...	6-[5-[(1~{R},2~{R},4~{S})-7-azabicyclo[2.2.1]heptan-2-yl]-2-fluoranyl-pyridin-3-yl]pyridine-3-carboxamide	non-polymer		312.3	10	Chemie (JC8)
3	F, C, J, G, D...	PHOSPHATE ION	non-polymer		95.0	15	Chemie (PO4)
4	B, I, J, F, C...	1,2-ETHANEDIOL	non-polymer		62.1	42	Chemie (EDO)
5	F, C, J, G, D...	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	10	Chemie (NAG)
6		water	water		18.0	659	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J: 1 - 236 (UniProt: Q8WSF8)

PDB	External Database	Details
Val 60	Ala 60	conflict
Val 155	Ala 155	conflict
Glu 237	-	expression tag
Asn 238	-	expression tag
Leu 239	-	expression tag
Tyr 240	-	expression tag
Phe 241	-	expression tag
Gln 242	-	expression tag
Gly 243	-	expression tag
His 244	-	expression tag
His 245	-	expression tag
His 246	-	expression tag
His 247	-	expression tag
His 248	-	expression tag
His 249	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	283267.5
Non-Polymers*	Number of molecules	77
	Total formula weight	9366.9
All*	Total formula weight	292634.4

*Water molecules are not included.