6QQM

Crystal structure of the alpha carbonic anhydrase from Schistosoma mansoni

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Putative carbonic anhydrase	polymer	300	34450.9	2	UniProt (G4VLX3) Pfam (PF00194) UniProt (by SIFTS) (A0A3Q0KSG2) In PDB	Schistosoma mansoni
2	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
5		water	water		18.0	389	Chemie (HOH)

Sequence modifications

A, B: 44 - 300 (UniProt: G4VLX3)

PDB	External Database	Details
Met 1	-	initiating methionine
Thr 2	-	expression tag
Tyr 3	-	expression tag
Gln 4	-	expression tag
Trp 5	-	expression tag
Leu 6	-	expression tag
Ile 7	-	expression tag
Gly 8	-	expression tag
Ile 9	-	expression tag
Gln 10	-	expression tag
Ile 11	-	expression tag
Ser 12	-	expression tag
Leu 13	-	expression tag
Leu 14	-	expression tag
Phe 15	-	expression tag
Val 16	-	expression tag
Asn 17	-	expression tag
Cys 18	-	expression tag
Ile 19	-	expression tag
Cys 20	-	expression tag
Asn 21	-	expression tag
Gly 22	-	expression tag
Ser 23	-	expression tag
Glu 24	-	expression tag
Trp 25	-	expression tag
Ser 26	-	expression tag
Tyr 27	-	expression tag
Thr 28	-	expression tag
Asn 29	-	expression tag
Ile 30	-	expression tag
Leu 31	-	expression tag
Thr 32	-	expression tag
Gly 33	-	expression tag
Pro 34	-	expression tag
Glu 35	-	expression tag
Thr 36	-	expression tag
Trp 37	-	expression tag
His 38	-	expression tag
Glu 39	-	expression tag
His 40	-	expression tag
Tyr 41	-	expression tag
Lys 42	-	expression tag
Asn 43	-	expression tag
Arg 299	Ser 256	conflict
Gly 300	Ser 257	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	68901.9
Non-Polymers*	Number of molecules	8
	Total formula weight	1199.8
All*	Total formula weight	70101.7

*Water molecules are not included.