6QL8

Cathepsin-K in complex with MIV-711

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cathepsin K	polymer	217	23737.7	1	UniProt (P43235) Pfam (PF00112) In PDB	Homo sapiens (Human)	Cathepsin O,Cathepsin O2,Cathepsin X
2	A	~{N}-[(2~{S})-1-[(3~{R},3~{a}~{R},6~{R},6~{a}~{R})-6-ethynyl-3-oxidanyl-2,3,3~{a},5,6,6~{a}-hexahydrofuro[3,2-b]pyrrol-4-yl]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-[5-fluoranyl-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide	non-polymer		569.7	1	Chemie (J5N)
3	A	NITRATE ION	non-polymer		62.0	6	Chemie (NO3)
4		water	water		18.0	260	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	23737.7
Non-Polymers*	Number of molecules	7
	Total formula weight	941.7
All*	Total formula weight	24679.4

*Water molecules are not included.