6QEH
CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX WITH AN INHIBITOR 5-Chloro-quinolin-8-ol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Methionine aminopeptidase 2 | polymer | 378 | 42470.2 | 1 | UniProt (P50579) Pfam (PF00557) In PDB | Homo sapiens (Human) | MetAP 2,Initiation factor 2-associated 67 kDa glycoprotein,p67eIF2,Peptidase M |
2 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
3 | A | 5-chloranylquinolin-8-ol | non-polymer | 179.6 | 1 | Chemie (HZQ) | |||
4 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
5 | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence modifications
A: 108 - 478 (UniProt: P50579)
PDB | External Database | Details |
---|---|---|
Met 107 | - | initiating methionine |
His 479 | - | expression tag |
His 480 | - | expression tag |
His 481 | - | expression tag |
His 482 | - | expression tag |
His 483 | - | expression tag |
His 484 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42470.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 381.6 | |
All* | Total formula weight | 42851.8 |