6QD7
EM structure of a EBOV-GP bound to 3T0331 neutralizing antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, K, L (L, Z, P) | Light chain | polymer | 214 | 23310.9 | 3 | Homo sapiens | ||
| 2 | B, I, J (H, X, U) | Heavy chain | polymer | 224 | 23673.6 | 3 | Homo sapiens | ||
| 3 | C, E, F (A, C, E) | Envelope glycoprotein,Virion spike glycoprotein,EBOV-GP1 | polymer | 322 | 34887.6 | 3 | UniProt (Q05320) Pfam (PF01611) | Ebola virus (ZEBOV) | GP1,2,GP |
| 4 | D, G, H (B, D, F) | Envelope glycoprotein | polymer | 168 | 18989.4 | 3 | UniProt (Q05320) Pfam (PF22307) | Ebola virus (ZEBOV) | GP1,2,GP |
| 5 | M, N, O (G, I, J) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G22573RC) | |||
| 6 | P, R, S (A, C, E) | alpha-D-mannopyranose | non-polymer | 180.2 | 3 | Chemie (MAN) | |||
| 7 | Q, T, U (B, D, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
A, C, E: 32 - 310 (UniProt: Q05320)
A, C, E: 470 - 508 (PDB: 6QD7)
B, D, F: 502 - 632 (UniProt: Q05320)
| PDB | External Database | Details |
|---|---|---|
| Gly 29 | - | expression tag |
| Ser 30 | - | expression tag |
| Arg 31 | - | expression tag |
| Ala 42 | Thr 42 | conflict |
B, D, F: 502 - 632 (UniProt: Q05320)
| PDB | External Database | Details |
|---|---|---|
| Gly 633 | - | expression tag |
| Ser 634 | - | expression tag |
| Gly 635 | - | expression tag |
| Tyr 636 | - | expression tag |
| Ile 637 | - | expression tag |
| Pro 638 | - | expression tag |
| Glu 639 | - | expression tag |
| Ala 640 | - | expression tag |
| Pro 641 | - | expression tag |
| Arg 642 | - | expression tag |
| Asp 643 | - | expression tag |
| Gly 644 | - | expression tag |
| Gln 645 | - | expression tag |
| Ala 646 | - | expression tag |
| Tyr 647 | - | expression tag |
| Val 648 | - | expression tag |
| Arg 649 | - | expression tag |
| Lys 650 | - | expression tag |
| Asp 651 | - | expression tag |
| Gly 652 | - | expression tag |
| Glu 653 | - | expression tag |
| Trp 654 | - | expression tag |
| Val 655 | - | expression tag |
| Leu 656 | - | expression tag |
| Leu 657 | - | expression tag |
| Ser 658 | - | expression tag |
| Thr 659 | - | expression tag |
| Phe 660 | - | expression tag |
| Leu 661 | - | expression tag |
| Gly 662 | - | expression tag |
| Thr 663 | - | expression tag |
| His 664 | - | expression tag |
| His 665 | - | expression tag |
| His 666 | - | expression tag |
| His 667 | - | expression tag |
| His 668 | - | expression tag |
| His 669 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 302584.2 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 2246.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1204.1 | |
| All* | Total formula weight | 306034.4 |
