6QAU
Crystal structure of ULK2 in complexed with MRT67307
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Serine/threonine-protein kinase ULK2 | polymer | 280 | 31767.7 | 3 | UniProt (Q8IYT8) Pfam (PF00069) | Homo sapiens (Human) | Unc-51-like kinase 2 |
| 2 | D, K, P (A, B, C) | N-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | non-polymer | 464.6 | 3 | Chemie (1FV) | |||
| 3 | E, F, G, H, L... (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 4 | I (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | J (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | R, S, T (A, B, C) | water | water | 18.0 | 174 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 276 (UniProt: Q8IYT8)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asp 173 | Thr 173 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 95303.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2080.0 | |
| All* | Total formula weight | 97383.1 |
