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6QAT

Crystal structure of ULK2 in complexed with hesperadin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DSerine/threonine-protein kinase ULK2polymer28031767.74UniProt (Q8IYT8)
Pfam (PF00069)
In PDB
Homo sapiens (Human)Unc-51-like kinase 2
2A, B, C, DN-{(3Z)-2-oxo-3-[phenyl({4-[(piperidin-1-yl)methyl]phenyl}amino)methylidene]-2,3-dihydro-1H-indol-5-yl}ethanesulfonamidenon-polymer516.74Chemie (FE7)
3waterwater18.018Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 276 (UniProt: Q8IYT8)
PDBExternal DatabaseDetails
Gly -3-expression tag
Gly -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Asp 173Thr 173conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight127070.9
Non-Polymers*Number of molecules4
Total formula weight2066.6
All*Total formula weight129137.5
*Water molecules are not included.

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PDB entries from 2024-10-16

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