6QAT
Crystal structure of ULK2 in complexed with hesperadin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Serine/threonine-protein kinase ULK2 | polymer | 280 | 31767.7 | 4 | UniProt (Q8IYT8) Pfam (PF00069) | Homo sapiens (Human) | Unc-51-like kinase 2 |
| 2 | E, F, G, H (A, B, C, D) | N-{(3Z)-2-oxo-3-[phenyl({4-[(piperidin-1-yl)methyl]phenyl}amino)methylidene]-2,3-dihydro-1H-indol-5-yl}ethanesulfonamide | non-polymer | 516.7 | 4 | Chemie (FE7) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 276 (UniProt: Q8IYT8)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asp 173 | Thr 173 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 127070.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2066.6 | |
| All* | Total formula weight | 129137.5 |
