6Q91
Structure of human galactokinase 1 bound with 5-Chloro-N-isobutyl-2-methoxybenzamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Galactokinase | polymer | 392 | 42210.0 | 4 | UniProt (P51570) Pfam (PF10509) Pfam (PF00288) Pfam (PF08544) | Homo sapiens (Human) | Galactose kinase |
| 2 | E, H, K (A, B, C) | beta-D-galactopyranose | non-polymer | 180.2 | 3 | Chemie (GAL) | |||
| 3 | F, I, L (A, B, C) | 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one | non-polymer | 350.4 | 3 | Chemie (HFK) | |||
| 4 | G, J, M, N (A, B, C, D) | 5-chloranyl-2-methoxy-~{N}-(2-methylpropyl)benzamide | non-polymer | 241.7 | 4 | Chemie (HR8) | |||
| 5 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 325 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 392 (UniProt: P51570)
| PDB | External Database | Details |
|---|---|---|
| His 1 | - | expression tag |
| Ala 252 | Lys 252 | engineered mutation |
| Ala 253 | Glu 253 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 168839.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2558.6 | |
| All* | Total formula weight | 171398.5 |
