6Q8P
Structure of CLK1 with bound N-methyl-10-nitropyrido[3,4-g]quinazolin-2-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Dual specificity protein kinase CLK1 | polymer | 339 | 39581.5 | 3 | UniProt (P49759) Pfam (PF00069) | Homo sapiens (Human) | CDC-like kinase 1 |
| 2 | D, F, G (A, B, C) | ~{N}-methyl-10-nitro-pyrido[3,4-g]quinazolin-2-amine | non-polymer | 255.2 | 3 | Chemie (HQB) | |||
| 3 | E (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 4 | H, I, J (A, B, C) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A, B, C: 148 - 484 (UniProt: P49759)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
| Ala 432 | Arg 432 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 118744.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 804.8 | |
| All* | Total formula weight | 119549.3 |
