6Q84
Crystal structure of RanGTP-Pdr6-eIF5A export complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Importin beta-like protein KAP122 | polymer | 1080 | 123492.6 | 2 | UniProt (P32767) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Karyopherin-122,Pleiotropic drug resistance regulatory protein 6 |
| 2 | B, E (B, E) | GTP-binding nuclear protein Ran | polymer | 176 | 20192.5 | 2 | UniProt (P62826) Pfam (PF00071) | Homo sapiens (Human) | Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein |
| 3 | C, F (C, F) | Eukaryotic translation initiation factor 5A-1 | polymer | 142 | 15526.7 | 2 | UniProt (P23301) Pfam (PF21485) Pfam (PF01287) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | eIF-5A-1,Hypusine-containing protein HP2,eIF-4D |
| 4 | G, I (B, E) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 5 | H, J (B, E) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
B, E: 5 - 180 (UniProt: P62826)
| PDB | External Database | Details |
|---|---|---|
| Leu 69 | Gln 69 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 318423.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1095.0 | |
| All* | Total formula weight | 319518.6 |
