6Q74
PI3K delta in complex with 1benzylN[5(3,6dihydro2Hpyran4yl)2methoxypyridin3yl]2methyl1Himidazole4sulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | polymer | 940 | 107823.7 | 1 | UniProt (O35904) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) In PDB | Mus musculus (house mouse) | PtdIns-3-kinase subunit delta,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta,p110delta |
| 2 | A | ~{N}-[5-(3,6-dihydro-2~{H}-pyran-4-yl)-2-methoxy-pyridin-3-yl]-2-methyl-1-(phenylmethyl)imidazole-4-sulfonamide | non-polymer | 440.5 | 1 | Chemie (HKN) | |||
| 3 | water | water | 18.0 | 220 | Chemie (HOH) |
Sequence modifications
A: 106 - 1044 (UniProt: O35904)
| PDB | External Database | Details |
|---|---|---|
| Gly 105 | - | expression tag |
| Gln 508 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 107823.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 440.5 | |
| All* | Total formula weight | 108264.2 |
