6Q4P
Fusidic acid bound AcrB_N298A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Multidrug efflux pump subunit AcrB | polymer | 1057 | 114693.3 | 3 | UniProt (P31224) Pfam (PF00873) | Escherichia coli K-12 | AcrAB-TolC multidrug efflux pump subunit AcrB,Acridine resistance protein B |
| 2 | D, E (D, E) | DARPin | polymer | 169 | 18317.6 | 2 | synthetic construct | ||
| 3 | F, FA, G, GA, H... (A, C, B) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 10 | Chemie (LMT) | |||
| 4 | J, JA, U (A, C, B) | DODECANE | non-polymer | 170.3 | 3 | Chemie (D12) | |||
| 5 | K, LA, MA, NA, W... (A, C, B) | DECYLAMINE-N,N-DIMETHYL-N-OXIDE | non-polymer | 201.3 | 6 | Chemie (DDQ) | |||
| 6 | DA, L, M, N, TA... (B, A, C, E) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 7 | O, VA (A, C) | HEXANE | non-polymer | 86.2 | 2 | Chemie (HEX) | |||
| 8 | S (B) | FUSIDIC ACID | non-polymer | 516.7 | 1 | Chemie (FUA) | |||
| 9 | IA, T (C, B) | PHOSPHATIDYLETHANOLAMINE | non-polymer | 734.0 | 2 | Chemie (PTY) | |||
| 10 | V (B) | (2S)-3-hydroxypropane-1,2-diyl didecanoate | non-polymer | 400.6 | 1 | Chemie (DDR) | |||
| 11 | OA, Y, Z (C, B) | N-OCTANE | non-polymer | 114.2 | 3 | Chemie (OCT) | |||
| 12 | AA, PA, QA, RA, SA (B, C) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 13 | BA, CA (B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 14 | EA (B) | DECANE | non-polymer | 142.3 | 1 | Chemie (D10) | |||
| 15 | KA (C) | TETRADECANE | non-polymer | 198.4 | 1 | Chemie (C14) | |||
| 16 | UA (C) | 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | non-polymer | 208.3 | 1 | Chemie (ETE) | |||
| 17 | AB, BB, XA, YA, ZA (D, E, A, B, C) | water | water | 18.0 | 522 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 1049 (UniProt: P31224)
| PDB | External Database | Details |
|---|---|---|
| Ala 298 | Asn 298 | engineered mutation |
| Leu 1050 | - | expression tag |
| Glu 1051 | - | expression tag |
| His 1052 | - | expression tag |
| His 1053 | - | expression tag |
| His 1054 | - | expression tag |
| His 1055 | - | expression tag |
| His 1056 | - | expression tag |
| His 1057 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 380715.0 | |
| Non-Polymers* | Number of molecules | 44 |
| Total formula weight | 11196.5 | |
| All* | Total formula weight | 391911.5 |
