6Q3W
Structure of human galactokinase 1 bound with Ethyl 1-(2-pyrazinyl)-4-piperidinecarboxylate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Galactokinase | polymer | 391 | 42071.8 | 4 | UniProt (P51570) Pfam (PF10509) Pfam (PF00288) Pfam (PF08544) | Homo sapiens (Human) | Galactose kinase |
| 2 | E, G, I (A, B, C) | beta-D-galactopyranose | non-polymer | 180.2 | 3 | Chemie (GAL) | |||
| 3 | F, H, K (A, B, C) | 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one | non-polymer | 350.4 | 3 | Chemie (HFK) | |||
| 4 | J (C) | ethyl 1-pyrazin-2-ylpiperidine-4-carboxylate | non-polymer | 235.3 | 1 | Chemie (HGE) | |||
| 5 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 641 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 392 (UniProt: P51570)
| PDB | External Database | Details |
|---|---|---|
| Ala 252 | Lys 282 | conflict |
| Ala 253 | Glu 283 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 168287.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1827.0 | |
| All* | Total formula weight | 170114.3 |
