6Q2M
Crystal structure of Photinus pyralis Luciferase Pps6 mutant in complex with DLSA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Luciferin 4-monooxygenase | polymer | 555 | 61234.4 | 3 | UniProt (P08659) Pfam (PF00501) Pfam (PF13193) | Photinus pyralis (Common eastern firefly) | Luciferase |
| 2 | D, IA, JA, X, Y... (A, C, B) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 3 | E, F, KA, LA (A, C) | (2S,5S)-hexane-2,5-diol | non-polymer | 118.2 | 4 | Chemie (DYD) | |||
| 4 | AA, AB, BA, BB, CA... (B, C, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 39 | Chemie (EDO) | |||
| 5 | CB, HA, W (C, B, A) | 5'-O-[N-(DEHYDROLUCIFERYL)-SULFAMOYL] ADENOSINE | non-polymer | 606.6 | 3 | Chemie (SLU) | |||
| 6 | DB, EB, FB (A, B, C) | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 550 (UniProt: P08659)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asn 214 | Thr 214 | engineered mutation |
| Cys 222 | Ala 222 | engineered mutation |
| Phe 255 | Tyr 255 | engineered mutation |
| Thr 276 | Ser 276 | engineered mutation |
| Asn 332 | His 332 | engineered mutation |
| Asn 354 | Glu 354 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 183703.3 | |
| Non-Polymers* | Number of molecules | 52 |
| Total formula weight | 5289.6 | |
| All* | Total formula weight | 188992.9 |
