6Q0M
Structure of Erbin PDZ derivative E-14 with a high-affinity peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Erbin | polymer | 94 | 10207.6 | 2 | UniProt (Q96RT1) Pfam (PF00595) In PDB | Homo sapiens (Human) | Densin-180-like protein,Erbb2-interacting protein,Protein LAP2 |
| 2 | C, D | peptide | polymer | 7 | 975.0 | 2 | synthetic construct | ||
| 3 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | B | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 92 (UniProt: Q96RT1)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Met 2 | - | expression tag |
| Ile 14 | Leu 1280 | engineered mutation |
| Arg 17 | Ser 1283 | engineered mutation |
| Ala 19 | Ser 1285 | engineered mutation |
| Ser 42 | Gln 1308 | engineered mutation |
| Leu 70 | His 1336 | engineered mutation |
| Ile 74 | Val 1340 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 22365.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 339.1 | |
| All* | Total formula weight | 22704.4 |
