6Q0D
CRYSTAL STRUCTURE OF LDHA IN COMPLEX WITH COMPOUND NCGC00384414-01 AT 2.05 A RESOLUTION
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | L-lactate dehydrogenase A chain | polymer | 332 | 36734.7 | 6 | UniProt (P00338) Pfam (PF00056) Pfam (PF02866) | Homo sapiens (Human) | LDH-A,Cell proliferation-inducing gene 19 protein,LDH muscle subunit,LDH-M,Renal carcinoma antigen NY-REN-59 |
| 2 | BA, G, K, O, R... (F, A, B, C, D...) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
| 3 | CA, H, L, P, S... (F, A, B, C, D...) | 2-{3-[3-(cyclopentylethynyl)-4-fluorophenyl]-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid | non-polymer | 622.7 | 6 | Chemie (P8M) | |||
| 4 | DA, I, M, Q, T... (F, A, B, C, D...) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 6 | Chemie (NAI) | |||
| 5 | AA, J, N, U, V... (F, B, C, E) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 6 | EA, FA, GA, HA, IA... (A, B, C, D, E...) | water | water | 18.0 | 754 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 220408.0 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 8851.3 | |
| All* | Total formula weight | 229259.3 |
