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6PZT

cryo-EM structure of human NKCC1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(B, A)
Solute carrier family 12 member 2polymer1212131668.52UniProt (P55011)
Pfam (PF08403)
Pfam (PF00324)
Pfam (PF03522)
Homo sapiens (Human)Basolateral Na-K-Cl symporter,Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2
Sequence modifications
B, A: 1 - 1212 (UniProt: P55011)
PDBExternal DatabaseDetails
Asn 289Lys 289engineered mutation
Arg 351Gly 351engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight263337.0
All*Total formula weight263337.0
*Water molecules are not included.

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PDB entries from 2026-01-28

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