6PZP
Crystal structure of caspase-1 in complex with VX-765
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Caspase-1 | polymer | 178 | 19869.8 | 1 | UniProt (P29466) Pfam (PF00656) In PDB | Homo sapiens (Human) | CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, IL-1 beta-converting enzyme, p45 |
| 2 | B | Caspase-1 | polymer | 88 | 10258.8 | 1 | UniProt (P29466) Pfam (PF00656) In PDB | Homo sapiens (Human) | CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, IL-1 beta-converting enzyme, p45 |
| 3 | A | N-(4-amino-3-chlorobenzene-1-carbonyl)-3-methyl-L-valyl-N-[(2S)-1-carboxy-3-oxopropan-2-yl]-L-prolinamide | non-polymer | 480.9 | 1 | Chemie (P7S) | |||
| 4 | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30128.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 480.9 | |
| All* | Total formula weight | 30609.5 |
