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6PZO

Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with YX-153

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Hdac6 proteinpolymer35739725.02UniProt (A7YT55)
Pfam (PF00850)
UniProt (by SIFTS) (F8W4B7)
Danio rerio (Zebrafish)Histone Deacetylase 6
2C, G
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
3D, E, H, I
(A, B)
POTASSIUM IONnon-polymer39.14Chemie (K)
4F, J
(A, B)
N-{[4-(hydroxycarbamoyl)phenyl]methyl}-2-(trifluoromethyl)pyridine-3-carboxamidenon-polymer339.32Chemie (P6Y)
5K, L
(A, B)
waterwater18.0656Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight79449.9
Non-Polymers*Number of molecules8
Total formula weight965.7
All*Total formula weight80415.7
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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