6PZD
Crystal structure of the neuraminidase stabilization mutant Y169aH from A/Shanghai/2/2013 (H7N9)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neuraminidase | polymer | 393 | 44014.0 | 1 | UniProt (V9NZ28) Pfam (PF00064) UniProt (by SIFTS) (R4NFR6) | Influenza A virus (A/Shanghai/02/2013(H7N9)) | |
| 2 | B (B) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1721.5 | 1 | In PDB GlyTouCan (G91704UR) | |||
| 3 | C, D, E, F, G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | H (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 5 | I (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | J (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | K (A) | water | water | 18.0 | 593 | Chemie (HOH) |
Sequence modifications
A: 82 - 468 (UniProt: V9NZ28)
| PDB | External Database | Details |
|---|---|---|
| Gly 77 | - | expression tag |
| Ser 78 | - | expression tag |
| Pro 79 | - | expression tag |
| Ser 80 | - | expression tag |
| Arg 81 | - | expression tag |
| His 169 | Tyr 166 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44014.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1721.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 766.9 | |
| All* | Total formula weight | 46502.4 |
